"We Really Don't Know How to Compute!" - Gerald Sussman (2011)Animations of unseeable biology | Drew Berry | TEDDNA animation (2002-2014) by Drew Berry and Etsuko Uno wehi.tv #ScienceArtmRNA Translation (Advanced)12 videos · 5 hr 39 min
Playlists

Biology for Programmers

Curated by Claude · 12 videos · 5 hr 39 min

HN commenters keep finding biology through computing: Sussman's talk on how we don't know how to compute, Levin's NeurIPS talk, a DEF CON talk on hacking the genome. This playlist starts with that framing, shows you the molecular machinery in animation, moves to Levin's idea that tissues compute shape, then to security, static analysis and DIY gene therapy, and ends with the Lisp hacker designing molecules.

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  1. 1
    Video frame: "We Really Don't Know How to Compute!" - Gerald Sussman (2011)1:04:19

    "We Really Don't Know How to Compute!" - Gerald Sussman (2011)

    Strange Loop Conference · Picked by 5 · 2022–2026

    The framing: Sussman sets biology's robustness against how brittle our programs are, and one commenter says it made them question what programming is.

  2. 2
    Video frame: Animations of unseeable biology | Drew Berry | TED9:09

    Animations of unseeable biology | Drew Berry | TED

    TED · Picked by 7 · 2017–2025

    Now look at the hardware: Drew Berry's accurate animations of DNA replication, which left one commenter in awe of the trillions of protein machines inside us.

  3. 3
    Video frame: DNA animation (2002-2014) by Drew Berry and Etsuko Uno wehi.tv #ScienceArt7:20

    DNA animation (2002-2014) by Drew Berry and Etsuko Uno wehi.tv #ScienceArt

    WEHImovies · Picked by 9 · 2020–2026

    Seven minutes of the same molecular machinery with no narration, jostling and mechanical, and the clip HN posts most often to show it.

  4. 4
    Video frame: mRNA Translation (Advanced)3:04

    mRNA Translation (Advanced)

    DNA Learning Center · Picked by 4 · 2014–2025

    Three minutes on the ribosome reading codons and assembling a protein, the clip HN posted widely in the mRNA-vaccine threads.

  5. 5
    Video frame: Electron transport chain7:45

    Electron transport chain

    Harvard Online · Picked by 6 · 2020–2024

    The power supply: proton pumps and ATP synthase as an actual rotary motor, which commenters share as the clearest example of nanomachines in cells.

  6. 6
    Video frame: The Evolution of Bacteria on a “Mega-Plate” Petri Dish (Kishony Lab)1:55

    The Evolution of Bacteria on a “Mega-Plate” Petri Dish (Kishony Lab)

    Harvard Medical School · Picked by 6 · 2016–2026

    Evolution as a search algorithm you can watch, as bacteria work their way across rising antibiotic doses in days.

  7. 7
    Video frame: Michael Levin: The electrical blueprints that orchestrate life | TED19:41

    Michael Levin: The electrical blueprints that orchestrate life | TED

    TED · Picked by 7 · 2021–2026

    Up from molecules to tissues: Levin's 20-minute introduction to the bioelectric layer, with two-headed worms and xenobots.

  8. 8
    Video frame: What Bodies Think About: Bioelectric Computation Outside the Nervous System - NeurIPS 201852:07

    What Bodies Think About: Bioelectric Computation Outside the Nervous System - NeurIPS 2018

    The Artificial Intelligence Channel · Picked by 12 · 2018–2024

    The full version given to an ML audience, and the talk that introduced many HN readers to Levin's view of cell collectives as computers that store pattern memories.

  9. 9
    Video frame: DEF CON 25 - John Sotos - Genetic Diseases to Guide Digital Hacks of the Human Genome49:47

    DEF CON 25 - John Sotos - Genetic Diseases to Guide Digital Hacks of the Human Genome

    DEFCONConference · Picked by 11 · 2017–2023

    The security engineer's view: genetic diseases as known exploits, a talk that convinced several commenters to keep their DNA out of databases.

  10. 10
    Video frame: Matt Might - Winning the War on Error Solving the Halting Problem and Curing Cancer48:36

    Matt Might - Winning the War on Error Solving the Halting Problem and Curing Cancer

    Curry On! · Picked by 3 · 2017–2019

    Static analysis and precision medicine in one talk, built on Might's search for his son's diagnosis, which commenters call a must-see.

  11. 11
    Video frame: I Genetically Engineered *MYSELF* to Fix Lactose Intolerance18:33

    I Genetically Engineered *MYSELF* to Fix Lactose Intolerance

    The Thought Emporium · Picked by 8 · 2018–2026

    Biology as a garage hack: a home-made AAV gene therapy tested on the host himself, the example HN keeps citing in biohacking threads.

  12. 12
    Video frame: Clasp: Common Lisp using LLVM and C++ for Molecular Metaprogramming57:38

    Clasp: Common Lisp using LLVM and C++ for Molecular Metaprogramming

    Google TechTalks · Picked by 8 · 2015–2024

    The closer: a chemist writes his own Lisp compiler to design molecules, and commenters dare anyone to watch it and not be impressed.